Fisher and his passenger, former "Basketball Wives" reality star Gloria Govan, were not injured.
The crash was reported shortly after 3 a.m. on the 101 West near the 405 Freeway interchange, according to the California Highway Patrol.
The 42-year-old former New York Knicks head coach was driving a 2015 Cadillac when the vehicle veered right and onto the paved right shoulder. The Cadillac continued across the right shoulder and hit the raised concrete curb and wood/metal guardrail.
The impact caused the Cadillac to overturn, and it came to rest on its roof, blocking two lanes of the northbound 101. Fisher and Govan, 32, were helped out of the vehicle unharmed.
No other vehicles were involved in the crash.
Officers discovered that Fisher had been drinking, the CHP said. He was arrested on suspicion of driving under the influence of alcohol without incident.
Fisher played in the NBA for nearly two decades, spending a majority of his career with the Lakers. He was an integral part of five NBA championships with the team.
After his playing career ended, Fisher was hired in June 2014 to be the first coach for Knicks President of Basketball Operations Phil Jackson.
The first season was the worst in franchise history with a 17-65 record, but the team played better early in the second season before Jackson fired Fisher last February with the Knicks in a 1-9 tailspin.
He has been working as an analyst for TNT as well as for Spectrum SportsNet's Lakers coverage this season.
City News Service and the Associated Press contributed to this report.