Flames shot through the roof as the children and two adults nervously watched. They all made their way out of the house, officials say.
Eyewitness News is told three of the children -- a three-week-old girl and three-month-old twin boys -- were taken to University Hospital to be checked for smoke inhalation. The other two were taken to a neighbor. The two adults in the house were uninjured.
The fire rousted 19 residents of the home. Some of them were staying with relatives, while the American Red Cross was requested for others.
The three-family house suffered heavy fire, smoke and water damages.