Starting for the second straight game, Toronto guard T.J. Ford had 10 points and nine assists.
Jamal Crawford scored 26 and Jared Jeffries had 21 points and 10 rebounds for the Knicks, who have won just two of their past 15 games. Quentin Richardson added 20 points and 10 rebounds while David Lee had 15 and 12 for New York.
Knicks forward Zach Randolph missed the game because of flu-like symptoms.
Andrea Bargnani scored 12 points as the Raptors handed New York its eighth straight loss in Toronto. The Knicks' last win north of the border came March 5, 2004.
Leading 32-23 after the first, Toronto widened the gap to 44-30 at 5:43 on a follow dunk by Bargnani. Two baskets by Jeffries and a pair of 3-pointers by Crawford keyed a 14-3 New York run over the next five minutes before a Bosh jumper gave the Raptors a 49-44 edge at the intermission.
A rare 3-pointer by Bosh, his fifth of the season, at 3:22 of the third, gave Toronto a 71-59 edge. The Raptors led 76-68 heading into the fourth.
