They say the plane came to rest with its wheels on a grassy area off the runway.
FAA spokeswoman Elizabeth Isham Cory says American flight 268 was en route from Seattle-Tacoma in Washington state to New York's JFK International Airport when a cockpit indicator light alerted pilots to a problem.
The plane was diverted to O'Hare and landed at 1:42 p.m.
The plane blew a tire while making its landing at O'Hare.
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