Semin had two goals for Washington, which lost for the first time in four games since dropping its season opener Oct. 10 in Atlanta. Mike Green also scored.
Petr Vrana scored in his NHL debut for the Devils, who finished 3-1 on a four-game road trip. Patrik Elias picked up his 365th assist on the goal, moving ahead of Scott Niedermayer and into sole possession of first place on the franchise's career list. Parise and Andy Greene also tallied in regulation.
Washington converted a two-man advantage midway through the second period to take a 2-1 lead. Green sneaked down the inside edge of the left circle to bat in a nice drop pass from Brooks Laich at 12:18.
Parise then had a nice stretch to get the Devils the lead. With Chris Clark off for tripping in the third, he tied it with 9:26 remaining on a shot at the right post. Just 1:08 later, he set up Greene's goal from the left point.
Semin was credited with his team-leading sixth goal with 5:11 left when his right-side drive caromed off the chest of defenseman Mike Mottau's chest and past Brodeur.
