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Heavy smoke and flames poured from the two-story warehouse at 56-96 49th Street in the Maspeth section.
Two of the firefighters were listed in serious condition at Elmhurst Hospital. One suffered a broken leg, while the other suffered head lacerations.
The third firefighter was listed in stable condition, but the nature of his injury was not released.
A worker told Eyewitness News reporter Lucy Yang that the warehouse contained nursing home supplies.
The fire was still burning late into the night.
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