Eyewitness News is told the 26-year-old victim was found by her 22-year-old husband when he returned to their 58th Street apartment from work at around 4 a.m.
She had been stabbed multiple times in the chest and was pronounced dead at the scene.
Police say a knife was recovered at the murder scene, an apartment inside a multi-family house.
Detectives taped off the house as they searched the area for evidence.
Police sources tell Eyewitness News that the woman's husband is at the precinct talking to detectives.
He is not considered to be a suspect -- but they are asking him some background details about when he found his wife dead.
NEW YORK AND TRI-STATE AREA NEWS