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The fire broke out on the first floor of the Waverly Street house just after 1:15 a.m. this morning.
Firefighters rushed into the building, which had window guards, to battle the blaze.
Fire officials say three of the firefighters were trapped on the third floor and were forced to jump out the window.
Joyce, the most seriously injured firefighter was rushed to St. Joseph's Medical Center in Yonkers, where he was pronounced dead.
Meanwhile, two other firefighters were taken to Jacobi Medical Center in the Bronx with serious but non life threatening injuries.
The fire was put out and the cause was under investigation. Eyewitness News is told the fire appears suspicious.
The Red Cross was helping four families with a total of 15 people with emergency lodging, clothing and food.
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