They were last seen leaving their home on Parsons Boulevard in Jamaica.
Erik is described as 4'10, 110 lbs, wearing a blue collared shirt with orange writing, blue jeans and brown boots.
Bryana is described as approximately 5'9, 185 lbs wearing purple jacket, black shirt with green neon writing, black dickie pants and purple and black sneakers.
Anyone with information on the whereabouts of the missing siblings is asked to call Crime Stoppers at 1-800-577-TIPS (8477).
The public can also submit their tips by logging onto the CRIME STOPPERS website at WWW.NYPDCRIMESTOPPERS.COM or by texting their tips to 274637(crimes) then enter TIP577.
All calls are strictly confidential.