It happened near the intersection of Dumont and Rockaway Avenues just after 6 p.m.
According to witnesses, the car was heading east on Dumont Avenue when it jumped the curb and hit the pedestrians.
It continued east on Dumont and hit two parked cars.
A 12-year-old girl, a 15-year-old boy, and a 16-year-old boy were all taken to Brookdale Hospital.
Two of the injured are in serious condition.