Marc Higgins, who is 21, is being held on $2 million bond.
Bristol police say he fatally attacked an unidentified 21-year-old Bristol man.
Police responded to a call to a house at 11 p.m. Saturday and found that four people had been stabbed.
The conditions of the three others, who also were not identified, were not immediately known.
Bristol police and State Police are investigating.
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