The 911 call came in at around 4 a.m. after two people were hit following a dispute outside a club near 35-35 Steinway Street in Astoria.
Police say driver of the vehicle fled the scene after the victims were struck.
It is not clear if the driver was involved in the fight but police believe it was a case of hit and run.
Two people have been arrested in connection with the assault and third person was injured as a result of the assault.
All three victims were taken to Elmhurst Hospital.
Anyone with information is asked to call police at 1-800-577-TIPS