The accident happened at about 11:30 Saturday morning, when the tanker truck carrying 12,000 gallons of gasoline overturned.
The truck crashed on a ramp of the Hutch that leads to the Cross Bronx Expressway.
Two of the truck's five fuel tanks were leaking fuel.
The FDNY had a foam line in operation to contain the spill.
By Saturday evening, the tanker had been turned upright and towed away, but firefighters say it could have been a very dangerous situation.
"We're a little lucky here, it's a desolated area back here on the interchange as far as houses and adjacent buildings," said Deputy Chief Edward Baggott of the FDNY. "But there is always the possibility of explosion, which has happened in this area years ago."
The fuel truck company sent a second tanker truck to the scene, so the remaining fuel could be offloaded.
The accident snarled traffic for miles, creating huge tie-ups throughout the day.
The driver of the tanker was taken to the hospital with non life-threatening injuries.
It's not yet known how many gallons of fuel leaked out.
Get Eyewitness News Delivered