Investigators say 79-year-old James Jackson was shot in the neck in his apartment on Gates Avenue in the Bushwick section early Sunday morning.
He died at the hospital a short time later.
Police are also looking for suspects in a shooting that claimed the life of a 37-year-old man in Brownsville.
NYPD officers were responding to a robbery report on Sunday afternoon when they found the man with a chest wound.
Police say Omar Murray was pronounced dead at Brookdale hospital.
No arrests have been made in either incident.
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