The bloody scene developed at the Madaba Deli on Huguenot Street and Centre Avenue around 12:30 a.m.
Police say two suspects, a man and a woman in their 20s, entered the business and held up the clerks.
It's unclear how the gunfire came about, but a 42-year-old employees was shot in the leg before the suspects fled without any cash.
On the way out of the store, the suspects tried to rob someone else, as well. But the 34-year-old resisted, and the gunman and his accomplice ran off empty handed.
The victim was taken to the hospital in stable condition with a graze wound and is expected to be okay.
Anyone with information on the suspects is asked to call authorities.