It happened just before 11:30 p.m. at the intersection of York Avenue and East 84th Street.
The victim was identified as Kelly Gordon, of Brielle, New Jersey.
Police say she was crossing York when she was struck by a taxi driver. Another cab driver heading in the opposite direction then ran over her.
EMS responded and transported the female to NY Cornell Hospital where she was pronounced DOA.
Both drivers remained at the scene.
The investigation is ongoing.