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Republican Donald Trump and Democrat Hillary Clinton were the projected winners in their parties' primaries in Georgia, Alabama, Virginia, Arkansas and Tennessee.
Clinton also picked up wins in Texas, Massachusetts, and American Samoa, while Trump carried the GOP contest in Massachusetts and Vermont.
Clinton's opponent Bernie Sanders won in Oklahoma, Colorado, Minnesota, and captured his home state of Vermont.
Republican Ted Cruz won the presidential primaries in Texas, Oklahoma and Alaska. Republican Marco Rubio picked up a win in Minnesota.
Each party held contests in 12 states. Democrats also voted in American Samoa.
Republicans will allocate 595 delegates from the results of Super Tuesday, nearly half of the 1,237 needed for the nomination.
Democrats will allocate 865, more than one-third of the necessary 2,383.
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