The announcement was made on Friday, and will go into effect on Sunday, May 3 until further notice.
Amtrak will close its concourse, which resides on the upper level of the station by 8th Avenue between 31st and 33rd Street, at 12 a.m., and NJ Transit will close its concourse at 1 a.m.
The station will reopen in full at 5 a.m.
Commuters who use overnight NJ Transit trains will still be allowed through the station.
A city bus will be provided for any homeless people who want to be taken to a shelter.
This comes on the heels of the MTA's announcement on Thursday that it will suspend subway service each night from 1 a.m. to 5 a.m beginning on Wednesday, May 6.
MORE CORONAVIRUS COVID-19 COVERAGE
COVID-19 Help, Information and Resources
Grieving the lost: Tri-State residents who have died
New York state
Share your coronavirus story with Eyewitness News
Stimulus check scams and other coronavirus hoaxes
Coronavirus prevention: how clean are your hands?
Centers for Disease Control and Prevention on coronavirus
Total count of NYC COVID-19 cases based on patient address