The two victims are 25-year-old Mario Guevera and 24-year-old Heather Acosta, both from Union City. They were pronounced dead at the scene.
Both were passengers in the rear seat of one of the cars.
The drivers and front-seat passengers of both cars were taken to Jersey City Medical Center for treatment of non-life threatening injuries, according to police.
Video from the scene showed both cars completely totaled with one of them flipped upside down.
The accident happened at about 3 a.m. on Tonnelle Avenue between North Street and Manhattan Avenue.
The investigation into the circumstances of the crash is ongoing.
Anyone with information is asked to contact law enforcement at 201-915-1345.
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