Video from the Citizen app showed flames on the 19th floor of the building at Concourse Village East in Melrose.
The fire broke out just after 5:45 a.m. Friday.
At least two people were being treated for minor injuries.
There was no immediate word what caused the fire.
ALSO READ | 2 men slashed in arms by suspect with dog on Harlem subway platform
* More Bronx news
* Send us a news tip
* Download the abc7NY app for breaking news alerts
* Follow us on YouTube
Submit a News Tip