The flames broke out inside the one-story building around 7:30 p.m. on 37th Street in the Sunnyside section. The building eventually experienced a partial roof collapse.
It was enormous. A churning, devouring fire that danced and weaved its way across the rooftops and defied the ocean of water dumped on it by firefighters.
The fire destroyed the facility used by a commercial and residential interior woodworking design and building company called New York Custom Interior Millwork Corp.
More than 150 firefighters responded to the punishingly hot scene.
The NYC Health Department is advising people in the area avoid smoke exposure from structural fires by closing windows while indoors and reducing outdoor activity where smoke is present.
Two firefighters have suffered minor injuries.
Firefighters are expected to battle the fire into the morning to try to contain fire.