The incident happened at 12:30 on 110th Street and 3rd Ave in Harlem.
Police say the pedestrian was crossing the road when he was fatally struck causing the driver to eventually lose control of the vehicle and flipping over two blocks further.
RELATED: FDNY responds to reports of pedestrians struck during protest in Manhattan
The driver then fled the scene.
According to at least one eyewitness, the Honda Accord was speeding and running red lights moments before the crash.
Family identified the victim as 52-year-old Manuel Encalada.
His family said he was on his way home after working the night shift when he was struck.
"I have no words to express, I just want justice. I want them to catch this person and put him in jail for so many years so people can be conscious and grateful to humanity," Encalada's life partner, Ana Villa, said.
COVID NEWS: Which businesses and activities have been traced to outbreaks?
* More Manhattan news
* Send us a news tip
* Download the abc7NY app for breaking news alerts
*Follow us on YouTube