Porzingis tested his knee before the game but was ruled out by the team approximately 90 minutes before tipoff.
Porzingis originally suffered the knee injury in the first half of Thursday's win over the Brooklyn Nets. The 22-year-old twisted his left knee when he received the ball in the post. He continued to play but then pulled himself out of the game early in the third quarter.
The Knicks appear to be taking a cautious approach with the injury, which is not expected to sideline Porzingis for an extended period.
He's officially listed as day-to-day and his status for the Knicks' next game -- againstBostonon Thursday -- is unknown at this point.
The Knicks (16-14) are 2-5 in games that Porzingis missed due to injury (that record includes their win over the Miami Heat on Nov. 29, in which Porzingis exited three minutes into the first quarter with an ankle injury). New York beat the Oklahoma City Thunder on Saturday without Porzingis and its second-leading scorer, Tim Hardaway Jr., who is out indefinitely with a stress injury in his lower left leg.
Porzingis and Hardaway Jr. are averaging a combined 43 points per game. Porzingis has been off to a strong start in his third season, averaging 25.5 points, 6.6 rebounds and 2.1 blocks.
ESPN's Ian Begley contributed to this report.