Officials say the accident occurred shortly after 7 p.m. on Rodney Street and South 3 Street in Williamsburg.
They say a 29-year-old man was driving a Toyota and side-swiped five vehicles before striking a postal truck and overturning.
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Citizen App video showed the scene and the overturned vehicle moments after the crash.
The victim was taken to Bellevue Hospital where he was pronounced dead.
It's unknown if anyone else was injured.
The investigation is ongoing.
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