The music venue closed its doors for the final time, with management citing rising rents.
The B.B. King Blues Club has been in business for 18 years and played host to Aretha Franklin, James Brown and Jay-Z.
Sunday's final show was blues legend Buddy Guy.
Several fans say they are upset the venue has been forced to shutter its doors.
The club says it is looking for a new location in Manhattan.
----------
* More Manhattan news
* Send us a news tip
* Download the abc7NY app for breaking news alerts