It happened inside an apartment near Marion Avenue and East 201 Street in the Bedford Park section Sunday at 2 p.m.
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The residents say the two men knocked on the door pretending to be UPS delivery men.
Police say a woman answered the door and the men forced their way in holding a knife to her stomach.
They then tied her up, along with a second woman and a 64-year-old man before headed to the bedroom of a 27-year-old man.
The 27-year-old was stabbed in the thigh and tied him up.
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Police say the men got away with two chains and $16,000 in cash from the victims room.
Anyone with information in regards to this incident is asked to call the NYPD's Crime Stoppers Hotline at 1-800-577-TIPS (8477) or for Spanish, 1-888-57-PISTA (74782).
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