39-year-old Abel Pina is facing several charges, including driving while impaired and driving without a license.
Eyewitnesses say he ignored their screams to stop and rammed a Dodge minivan into cyclists who were taking part in the NYC Century Bike Tour and were stopped at a red light at 12th Avenue and 39th Street in Borough Park.
The driver tried to run away according to eyewitnesses, but someone grabbed him.
Authorities say a 55-year-old woman from Queens is in critical condition.