The FDNY received a call around 8:20 p.m. for a fire at a building on White Plains Road in the Wakefield section.
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Officials say the fire went to a second alarm at 8:23 p.m. and then spread to a third alarm around 8:45 p.m.
According to the FDNY, the fire has since spread to a fourth alarm.
Two firefighters suffered injuries. One refused medical attention and the other was taken to a local hospital.
Officials say firefighters remain on the scene and the fire is not under control at this time.
No fire extended into adjacent buildings.
Due to FDNY activity, the 2 train was temporarily suspended between 219th Street and 241st Street, but has resumed.
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So far, no major injuries have been reported.
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