Firefighters responded to reports of a fire at 3044 Wallace Ave., where flames broke out in the basement of the six-story apartment building just minutes before 10 p.m.
The fire was placed under control about a half hour later.
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Authorities say one person was taken to the hospital in serious condition.
Three other individuals, including a firefighter, suffered minor injuries.
All victims were taken to Jacobi Medical Center.
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The cause of the fire in under investigation.
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