The fire was reported at 1414 Bryant Avenue around 12:20 p.m.
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The fire was on the first floor of a three-story multi-family home, which left some people trapped on the higher floors.
Residents told Eyewitness News that smoke quickly filled the building and it was terrifying.
Some managed to jump onto the roof of an adjacent home, but residents in the rear of the building had to wait for a firefighter while others tried to cut through a series of fences to put ladders in position.
"Two civilians were on the third floor at the rear window, we had difficulty gaining access with ladders to the rear of the structure. We started to set up for a roof rope rescue operation in case we had to pick them up from the window. Luckily we didn't need to do this, we were able to knock the fire down and bring the people down the interior stairs," said FDNY Captain Hugh Duffy.
Officials say approximately 106 fire and EMS members responded and the fire was extinguished shortly after 1 p.m.
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Seven people were evaluated at the scene for minor injuries but declined medical attention.
The cause of the fire is under investigation.
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