The incident was reported around 6:45 p.m. on Thursday in front of 1551 Sheridan Ave.
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The children, a 10-year-old girl and her 5-year-old brother, somehow avoided being shot as the gunman fired multiple shots on his intended target, a 24-year-old man.
The suspect fired about a dozen shots in total.
The victim was shot three times -- once in each leg and in the lower back -- and taken to the hospital, where he is expected to survive.
The children were not physically injured.
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WARNING: The following video is shocking -- everyone involved survived
Kids miraculously not hit in brazen broad daylight shooting on NYC sidewalk
After the shooting, the suspect got on a scooter with a second person and they both got away northbound on Sheridan Avenue.
NYPD Chief of Department Rodney Harrison said the shooting "seems like it's a gang incident, which has been plaguing NYC this year."
"I'm disgusted, I'm going to be honest with you, it's very alarming," Harrison said.
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Anyone with information is asked to call the NYPD's Crime Stoppers Hotline at 1-800-577-TIPS (8477) or for Spanish, 1-888-57-PISTA (74782).
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