The crash was reported at West 82nd Street and Amsterdam Avenue around noon.
The M11 bus was traveling northbound on Amsterdam Avenue at 11:22 a.m. when a truck in the next lane attempted to avoid a car that swerved into its lane and clipped the front of the bus.
The bus driver, a 25-year veteran, slammed on the brakes. He and about 11 people on the bus were checked out.
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They were taken to Mount Sinai West or Mount Sinai Morningside, all with non-life-threatening injuries.
The circumstances surrounding the crash were not yet known.
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