The incident was reported Friday at 5:30 p.m. at 164th Street and Jamaica Avenue.
Police say the driver of a Range Rover traveling southbound on 164th Street lost control of the vehicle and struck the pedestrians.
Witnesses say the SUV slammed into a pole before hitting the woman and child.
"People were screaming, people were gathering, creating crowds around the body," witness Junior Rodriguez said.
Both of the victims were taken to Jamaica Hospital where they were pronounced deceased.
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The victims were not related.
"It was tragic, blood everywhere on floor, you can imagine that being your child," witness Mohamed Trore said.
Police say the driver of the car, a 47-year-old woman, remained on the scene. Witnesses said she was clearly upset.
It is unknown if anyone else was in the vehicle at the time of the incident.
No criminality is suspected at this time, but the investigation is ongoing.
The victims identities have not yet been released, but Mayor Bill de Blasio offered his condolences to the victims' families.
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