The crash happened just after 3 p.m., according to the Federal Aviation Administration.
State troopers located the single-engine Cessna 172 in a state park near Lake Kemah after the FAA issued an alert for the missing aircraft.
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The aircraft departed from Essex County Airport for Sussex Airport.
There are two confirmed fatalities.
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The FAA and National Transportation Safety Board will be investigating what led to the crash.
Few other details were released. This story will be updated as more information becomes available.
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