The flames broke out around 4 p.m on the top floor of six-story building on Linden Boulevard in East Flatbush.
The FDNY says three victims were rushed to Kings County Hospital. A woman is listed in critical condition while the two children are in stable condition.
Authorities say one of the victims was found in a hallway that leads to the bedroom, while the other two were located in the bedroom.
No firefighters were injured.
----------
* More Brooklyn news
* Send us a news tip
* Download the abc7NY app for breaking news alerts
* Follow us on YouTube