The shooting happened just before 7 p.m. at 17 Louisiana Ave. between Williams Avenue and Hegeman Street in East New York.
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A woman was shot several times and was pronounced dead at the scene.
A 26-year-old was also shot several times and is in critical condition at Brookdale Hospital.
Police believe the victims are mother and son.
Police have taken a person identified as a possible partner of the female victim into custody.
The circumstances that led up to the shooting were not immediately made clear.
The investigation into the shooting is ongoing. No other injuries were reported.
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