The fire was reported at a building at 874 Jefferson Avenue just after 7 p.m.
Officials responded to the call for the fire on the second floor of a three-story building.
One additional civilian and one firefighter suffered serious, but non-life-threatening, injuries and were taken to the hospital.
The details surrounding the victim's death are not yet known.
The fire was under control shortly after 7:30 p.m.
The cause of the fire remains under investigation.
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