It happened at Columbus Avenue and West 105th Street just after 3:15 a.m.
29-year-old Nayquan Garden was shot in the chest.
He was taken to St. Luke's Hospital where he was pronounced dead.
The gunman fled on foot.
No arrests have been made at this time.
RELATED: Vigil held in response to NYC gun violence
----------
* Get Eyewitness News Delivered
* More Manhattan news
* Send us a news tip
* Download the abc7NY app for breaking news alerts
* Follow us on YouTube