The robbery happened at the store on West 14th St., in one of the city's busiest and trendiest neighborhoods, around noon.
The store had barely been open an hour when the thieves burst through the door.
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The suspects, two men and a woman, displayed a firearm and told everyone in the store to get down.
They took several pieces of luggage and other miscellaneous items worth thousands of dollars.
The thieves got away in a black Toyota with New York license plates westbound on 14th Street.
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The workers were not injured.
Tourists in the area said they couldn't believe the brazen robbery happened in the middle of the day.
"It's very daring and middle of the day for somebody to rob a very high-end store at gunpoint and put all the poor people there at risk, terrible," said Rosemary Welburn, a tourist from Australia.
Brooklyn resident Joe Salama says he and his family skipped the subway to avoid crime underground.
"So we came in to spend the day, you know? The kids are off from school today, it's a nice family day and that's, like, the last thing I would expect," Salama said. "We decided to drive and not take the subway because we felt like it wasn't maybe so safe. So I feel like things have deteriorated a little bit."
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