The restaurant, Guy's American Kitchen & Bar, served its last public meal Saturday. Restaurant officials held a private dinner event on New Year's Eve for its last night of operation.
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The restaurant opened in 2012, where it was greeted with a no-star review from The New York Times' restaurant critic.
Fieri said in a statement that he was proud of the restaurant serving millions of patrons for over five years, and did not give a reason for its closure.
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Reaction on social media has been interesting:
The restaurant was part of the Blue Stein Group, a New York collection of restaurants that includes the Heartland Brewery chain.