Suffolk County Police received the initial call at 6:13 a.m. after the crash involving two cars and the truck at Route 25 and Main Avenue in Lake Grove.
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The truck carrying nearly 4,000 gallons of home heating oil flipped over, causing a large fire that engulfed all three vehicles.
Everyone inside the vehicles was able to get out safely.
No significant injuries have been reported.
RAW VIDEO:
Accident sparks huge fire on Long Island
The fire was so big it knocked out power lines - causing outages in the area.
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Route 25 between Wood Road and Hawkins Road is expected to be closed all day for the investigation and cleanup.
Motorists are advised to avoid the area.
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