The house fire happened Sunday morning on Somerset Road in North Amityville.
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Investigators say they can't make a connection between the murder and fire.
On Friday, a shooting left a man dead at the same home.
Officers responded to the scene after a 911 caller reported a man had been shot, which occurred after an altercation. The shooter then fled the scene.
When officers arrived, they found Elbert Wright, 28, of Massapequa, dead from a gunshot wound.
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The investigation for both incidents are continuing.
Detectives are asking anyone with information on this incident to call the Homicide Squad at 631-852-6392 or anonymously to Crime Stoppers at 1-800-220-TIPS.
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