The incident happened just before 5 p.m. at 44th Street and Eighth Avenue.
Police believe a 24-year-old woman was injured by the debris that fell from InterContinental Hotel in Midtown.
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When officers arrived at the location, they found the victim with a laceration to her head.
She was taken to Bellevue Hospital in stable condition.
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Four juveniles were taken into custody for questioning, according to police sources. Three of the individuals have been released from custody.
The investigation is ongoing.
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