The incident happened just before 5 p.m. at 44th Street and Eighth Avenue.
Police believe a 24-year-old woman was injured by the debris that fell from InterContinental Hotel in Midtown.
When officers arrived at the location, they found the victim with a laceration to her head.
She was taken to Bellevue Hospital in stable condition.
Four juveniles were taken into custody for questioning, according to police sources. Three of the individuals have been released from custody.
The investigation is ongoing.
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