Chanel Lewis was accused of killing 30-year-old Karina Vetrano as she ran on a park trail in Howard Beach, Queens, in August 2016.
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Prosecutors say Vetrano was sexually abused and strangled. Her father found her body.
Lewis' first trial ended in a hung jury in November.
The Legal Aid Society stresses that Lewis "is presumed innocent."
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It says jurors must scrutinize the accuracy and reliability of statements police say they obtained from the defendant, and the reliability of DNA evidence.
Legal Aid also notes that prosecutors have a "burden of proof beyond a reasonable doubt."
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