The incident happened after 9 p.m. Monday on Amsterdam Avenue at 91st Street on the Upper West Side.
The 48-year-old man was rushed to St. Luke's Hospital with multiple stab wounds to his chest. He was pronounced dead from his injuries at the hospital.
His 44-year-old wife, Tracy McCarter, was arrested and charged with murder and criminal possession of a weapon.
The investigation into the incident is ongoing.
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