The victims were shot in a house on Fulton Avenue just after 10 p.m. Monday.
Two men and a woman are believed to have been killed. They were pronounced dead at the scene.
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One of the victims is believed to have been involved in drug activity. Investigators said the shooting appears to be the result of a drug robbery. Drugs and guns were recovered at the scene.
Police quickly surrounded a U-Haul truck parked on nearby Bayside Place that they said was connected to the shooting. Two men were reported to have fled that vehicle.
A man who identified himself as a friend of the woman who was shot, said she was pregnant and a mother.
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No arrests were made. The victims have not been identified.
The Hudson County Prosecutors Office is investigating the shooting. There was no immediate comment.