The driver lost control while northbound on Broad Street, jumping the curb.
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The vehicle careened through a utility pole, through the marquee, and into a tree.
The car came to a rest in the front of the Newark Boys Chorus building.
Two people in the car, including a four-month-old baby, were treated for non-life threatening injuries.
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The cause of the crash is under investigation.
The marquee outside the Newark Symphony Hall sustained significant damage. The building was added to the National Register of Historic Places in 1977.
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