State police say a Honda minivan veered off an exit ramp and crashed into a light pole just after 10 a.m.
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The driver, Robert Csapo, 46, and a male - both from Lyndhurst - were killed.
Two other boys in the car were injured and taken to a nearby hospital but are expected to survive.
Exit 53 Eastbound was closed for around four hours after the crash, which remains under investigation.
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