The fire broke out about 12:15 p.m. Saturday near the intersection of East Eighth Street and Avenue C in the Kensington section.
Sixty firefighters were called to the scene to put the fourth-floor fire out.
The condition and ages of the victims are currently unknown.
ALSO READ | NYC pediatrician overcomes challenges in Venezuela to inspire patients in the Bronx
NYC pediatrician overcomes challenges to inspire patients in the Bronx
----------
* More Brooklyn news
* Send us a news tip
* Download the abc7NY app for breaking news alerts
* Follow us on YouTube
Submit a tip or story idea to Eyewitness News
Have a breaking news tip or an idea for a story we should cover? Send it to Eyewitness News using the form below. If attaching a video or photo, terms of use apply.